Tbio METTL6 Methyltransferase-like protein 6

Protein Summary

Description

Probable methyltransferase.

Uniprot Accession IDs

• Q8TCB7
• Q96LU4

Gene Name

• METTL6

Ensembl ID

• ENST00000383789
• ENSP00000373299
• ENSG00000206562
• ENST00000383790
• ENSP00000373300
• ENST00000443029
• ENSP00000407613

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.95
histone modification site profile	0.88
transcription factor binding site profile	0.79
tissue sample	0.68
kinase perturbation	0.66

Protein Classes

PANTHER Classes

Protein / Transferase / Methyltransferase / Methyltransferase-like Protein 6

DTO Classes

Protein / Enzyme / Transferase / Methyltransferase / Methyltransferase-like Protein 6

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 119   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.82   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0