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Tbio
METTL17
Methyltransferase-like protein 17, mitochondrial

Protein Summary
Description
May be a component of the mitochondrial small ribosomal subunit.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339374
  • ENSP00000343041
  • ENSG00000165792
  • ENST00000382985
  • ENSP00000372445
  • ENST00000556670
  • ENSP00000450794

Symbol
  • METT11D1
  • METT11D1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.99
transcription factor binding site profile
0.82
histone modification site profile
0.77
interacting protein
0.69
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (72)
MRPS18B
Tbio
Novelty:  0.14519418
p_int:  0.981665012
p_ni:  0.018334988
Data Source:  BioPlex
HSPD1
Tbio
Novelty:  0.00018924
p_int:  0.974097618
p_ni:  0.025902382
Score:  0.161
Data Source:  BioPlex,STRINGDB
MRPS17
Tdark
Novelty:  0.46103276
p_int:  0.956053867
p_ni:  0.043946132
Data Source:  BioPlex
MCAT
Tbio
Family:  Enzyme
Novelty:  0.00600508
p_int:  0.89111442
p_ni:  0.10888558
Score:  0.273
Data Source:  BioPlex,STRINGDB
MRPS27
Tbio
Novelty:  0.22058227
p_int:  0.873806865
p_ni:  0.126193135
Score:  0.163
Data Source:  BioPlex,STRINGDB
PLA2G10
Tchem
Family:  Enzyme
Novelty:  0.00289317
p_int:  0.79073993
p_ni:  0.20926007
Data Source:  BioPlex
CHCHD1
Tbio
Novelty:  1.0101589
Score:  0.79
Data Source:  STRINGDB
LIPT2
Tbio
Family:  Enzyme
Novelty:  0.31022396
Score:  0.785
Data Source:  STRINGDB
LRPPRC
Tbio
Novelty:  0.01573276
Score:  0.776
Data Source:  STRINGDB
POP1
Tbio
Family:  Enzyme
Novelty:  2.92497626
Score:  0.748
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
1
3
77.1
testosterone measurement
2
1
2
76.3
hemoglobin measurement
2
1
2
74.8
red blood cell density measurement
1
1
1
69.4
platelet crit
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
77.1
testosterone measurement
2
76.3
hemoglobin measurement
2
74.8
red blood cell density measurement
1
69.4
platelet crit
1
54.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 17
VGNC:12560
738844
Macaque
methyltransferase like 17
705009
Mouse
MGI:1098577
52535
Rat
RGD:1559895
305845
Dog
methyltransferase like 17
475396
Species
Name
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 17
Macaque
methyltransferase like 17
Mouse
Rat
Dog
methyltransferase like 17
Publication Statistics
PubMed Score 3.08
PubMed score by year
PubTator Score 0.58
PubTator score by year
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Related Publications
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PMID
Year
Title