Protein Summary
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity). Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 [PubMed 15085178]).[supplied by OMIM, Mar 2008]
- ENST00000568223
- ENSP00000455068
- ENSG00000103260
- C16orf23
- C16orf23
- c380A1.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.81 | ||
PubMedID | 0.66 | ||
small molecule perturbation | 0.65 | ||
tissue sample | 0.65 | ||
cell type or tissue | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 29.02 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 89 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 29.02 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 89 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (61)
MGAT4C
Family: Enzyme
Novelty: 0.19680806
p_int: 0.999943598
p_ni: 0.000049896
p_wrong: 0.000006506
Data Source: BioPlex
A2M
Novelty: 0.00070446
p_int: 0.999916634
p_ni: 0.000002244
p_wrong: 0.000081122
Score: 0.221
Data Source: BioPlex,STRINGDB
DEFA5
Novelty: 0.00863727
p_int: 0.989725607
p_ni: 0.000065953
p_wrong: 0.01020844
Score: 0.183
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (3)
Components (1)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Disease Associations ()
GWAS Traits (20)
Items per page:
1 – 5 of 20
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 9 | 10 | 91.7 | |||||
BMI-adjusted waist circumference | 1 | 7 | 7 | 82.8 | |||||
cancer antigen 125 measurement | 1 | 3 | 3 | 77.9 | |||||
mean corpuscular volume | 1 | 1 | 1 | 74.6 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 72.3 | |||||
Items per page:
1 – 5 of 20
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 10 | 91.7 | |||||
BMI-adjusted waist circumference | 7 | 82.8 | |||||
cancer antigen 125 measurement | 3 | 77.9 | |||||
mean corpuscular volume | 1 | 74.6 | |||||
mean reticulocyte volume | 1 | 72.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (7)
1 – 5 of 7
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:1917333 | 70083 | ||||||
Rat | RGD:1306222 | 287151 | ||||||
Horse | meteorin, glial cell differentiation regulator | VGNC:20114 | 100147618 | |||||
Cow | meteorin, glial cell differentiation regulator | VGNC:31398 | 515528 | |||||
Pig | meteorin, glial cell differentiation regulator | 100519829 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Horse | meteorin, glial cell differentiation regulator | |||||
Cow | meteorin, glial cell differentiation regulator | |||||
Pig | meteorin, glial cell differentiation regulator | |||||
Publication Statistics
PubMed Score 29.02
PubMed score by year
PubTator Score 7.92
PubTator score by year
Related Publications
Text Mined References (7)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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