METAP2
Methionine aminopeptidase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.91 | ||
kinase perturbation | 0.88 | ||
disease perturbation | 0.87 | ||
virus perturbation | 0.83 | ||
drug | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Inactivation, recovery and regulation of the phototransduction cascade | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
Inactivation, recovery and regulation of the phototransduction cascade | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-UniRule | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-UniRule | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
C-reactive protein measurement | 4 | 5 | 5 | 95.6 | |||||
reticulocyte count | 7 | 3 | 7 | 93.4 | |||||
reticulocyte measurement | 3 | 3 | 3 | 93.4 | |||||
3 | 2 | 2 | 1 | 57.1 | |||||
sex hormone-binding globulin measurement | 4 | 2 | 4 | 39.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
C-reactive protein measurement | 5 | 95.6 | |||||
reticulocyte count | 7 | 93.4 | |||||
reticulocyte measurement | 3 | 93.4 | |||||
2 | 1 | 57.1 | |||||
sex hormone-binding globulin measurement | 4 | 39.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | methionyl aminopeptidase 2 | VGNC:13217 | 452141 | |||||
Macaque | methionyl aminopeptidase 2 | 712400 | ||||||
Mouse | MGI:1929701 | 56307 | ||||||
Rat | RGD:70995 | 64370 | ||||||
Dog | methionyl aminopeptidase 2 | VGNC:43168 | 475429 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | methionyl aminopeptidase 2 | |||||
Macaque | methionyl aminopeptidase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | methionyl aminopeptidase 2 | |||||
PMID | Year | Title |
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