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Tbio
MEA1
Male-enhanced antigen 1

Protein Summary
Description
May play an important role in spermatogenesis and/or testis development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000244711
  • ENSP00000244711
  • ENSG00000124733

Symbol
  • MEA
  • HYS
  • MEA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
transcription factor perturbation
0.74
tissue sample
0.68
transcription factor binding site profile
0.67
co-expressed gene
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 36.95   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 36.95   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
AP1M1
Tbio
Novelty:  0.029282
p_int:  0.999997166
p_ni:  0.000002835
Score:  0.188
Data Source:  BioPlex,STRINGDB
AP1B1
Tbio
Novelty:  0.03370208
p_int:  0.999995191
p_ni:  0.000004809
Data Source:  BioPlex
AP2M1
Tbio
Novelty:  0.00769368
p_int:  0.999464736
p_ni:  0.000535264
Score:  0.23
Data Source:  BioPlex,STRINGDB
AP2B1
Tbio
Novelty:  0.00921093
p_int:  0.959752399
p_ni:  0.040247601
Data Source:  BioPlex
AP2A1
Tbio
Novelty:  0.08554974
p_int:  0.948540797
p_ni:  0.051459203
Data Source:  BioPlex
PPP2R5D
Tbio
Family:  Enzyme
Novelty:  0.03990599
Score:  0.907
Data Source:  STRINGDB
KLHDC3
Tbio
Novelty:  0.63840156
Score:  0.907
Data Source:  STRINGDB
DPY30
Tbio
Novelty:  0.03098629
Score:  0.818
Data Source:  STRINGDB
NCAPD2
Tbio
Novelty:  0.04960987
Score:  0.812
Data Source:  STRINGDB
NUP153
Tbio
Novelty:  0.00696568
Score:  0.81
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
3
4
4
89.1
apolipoprotein A 1 measurement
4
4
5
86.9
high density lipoprotein cholesterol measurement
10
5
11
86.5
blood protein measurement
1
2
2
80.3
homocysteine measurement
1
1
1
71
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein B measurement
4
89.1
apolipoprotein A 1 measurement
5
86.9
high density lipoprotein cholesterol measurement
11
86.5
blood protein measurement
2
80.3
homocysteine measurement
1
71
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
male-enhanced antigen 1
VGNC:8170
472010
Macaque
male-enhanced antigen 1
699300
Mouse
MGI:96957
17256
Rat
RGD:1597751
685131
Dog
male-enhanced antigen 1
VGNC:43112
474906
Species
Name
OMA
EggNOG
Inparanoid
Chimp
male-enhanced antigen 1
Macaque
male-enhanced antigen 1
Mouse
Rat
Dog
male-enhanced antigen 1
Publication Statistics
PubMed Score 36.95
PubMed score by year
PubTator Score 21.08
PubTator score by year
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Related Publications
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PMID
Year
Title