You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MCUR1
Mitochondrial calcium uniporter regulator 1

Protein Summary
Description
Key regulator of mitochondrial calcium uniporter (MCU) required for calcium entry into mitochondrion (PubMed:23178883, PubMed:26445506, PubMed:27184846, PubMed:26976564). Plays a direct role in uniporter-mediated calcium uptake via a direct interaction with MCU (PubMed:23178883). Probably involved in the assembly of the membrane components of the uniporter complex (uniplex) (PubMed:27184846).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379170
  • ENSP00000368468
  • ENSG00000050393
  • ENST00000488770
  • ENSP00000476162

Symbol
  • C6orf79
  • CCDC90A
  • FMP32
  • C6orf79
  • CCDC90A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.7
transcription factor perturbation
0.68
cellular component
0.63
tissue sample
0.61
histone modification site profile
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.11   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 67   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.11   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 67   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0