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Tdark
MCRIP2
MAPK regulated corepressor interacting protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307650
  • ENSP00000305138
  • ENSG00000172366
  • ENST00000474840
  • ENSP00000433876

Symbol
  • C16orf14
  • FAM195A
  • FAM195A
  • C16orf14
  • c349E10.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.5   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.5   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
ATXN2
Tbio
Novelty:  0.00373116
p_int:  0.999999939
p_ni:  6.1e-8
Score:  0.266
Data Source:  BioPlex,STRINGDB
CCNDBP1
Tbio
Novelty:  0.01527762
p_int:  0.999994964
p_ni:  0.000002819
p_wrong:  0.000002218
Score:  0.403
Data Source:  BioPlex,STRINGDB
ATXN2L
Tbio
Novelty:  0.01996982
p_int:  0.999730532
p_ni:  0.000269468
Score:  0.445
Data Source:  BioPlex,STRINGDB
DDX6
Tbio
Family:  Enzyme
Novelty:  0.01032357
p_int:  0.998861216
p_ni:  0.001138784
Score:  0.429
Data Source:  BioPlex,STRINGDB
IL17F
Tbio
Novelty:  0.00223549
p_int:  0.998503522
p_ni:  0.001318874
p_wrong:  0.000177604
Data Source:  BioPlex
LSM12
Tbio
Novelty:  0.0593959
p_int:  0.997780893
p_ni:  0.002219107
Data Source:  BioPlex
CASC3
Tbio
Novelty:  0.03935581
p_int:  0.988254228
p_ni:  0.011745761
p_wrong:  1.2e-8
Data Source:  BioPlex
PAPSS1
Tbio
Family:  Enzyme
Novelty:  0.01784751
p_int:  0.984184795
p_ni:  0.015815204
p_wrong:  1e-9
Data Source:  BioPlex
GNG5
Tbio
Novelty:  0.1525101
p_int:  0.849647887
p_ni:  0.150340799
p_wrong:  0.000011314
Data Source:  BioPlex
ZNF280D
Tdark
Family:  TF
Novelty:  1.31551539
Score:  0.712
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (22)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
10
11
91.8
reticulocyte measurement
2
2
2
85.8
mean corpuscular volume
1
1
1
84
BMI-adjusted waist circumference
1
7
7
82.8
mean reticulocyte volume
1
2
2
81.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
11
91.8
reticulocyte measurement
2
85.8
mean corpuscular volume
1
84
BMI-adjusted waist circumference
7
82.8
mean reticulocyte volume
2
81.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
MAPK regulated corepressor interacting protein 2
VGNC:51595
745018
Mouse
MGI:1915491
68241
Rat
RGD:1592603
685545
Cow
MAPK regulated corepressor interacting protein 2
618020
Pig
MAPK regulated corepressor interacting protein 2
100525039
Species
Name
OMA
EggNOG
Inparanoid
Chimp
MAPK regulated corepressor interacting protein 2
Mouse
Rat
Cow
MAPK regulated corepressor interacting protein 2
Pig
MAPK regulated corepressor interacting protein 2
Publication Statistics
PubMed Score 1.50
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title