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Tdark
MCCD1
Mitochondrial coiled-coil domain protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000376191
  • ENSP00000365362
  • ENSG00000204511
  • ENST00000383512
  • ENSP00000373004
  • ENSG00000206447
  • ENST00000421209
  • ENSP00000389666
  • ENSG00000226923
  • ENST00000422733
  • ENSP00000407020
  • ENSG00000226841
  • ENST00000424816
  • ENSP00000399197
  • ENSG00000225228
  • ENST00000430073
  • ENSP00000407581
  • ENSG00000228662
  • ENST00000443405
  • ENSP00000402555
  • ENSG00000238238
  • ENST00000452195
  • ENSP00000392250
  • ENSG00000231975
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.72
trait
0.61
tissue
0.56
disease
0.52
cell line
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.43   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 7   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.43   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 7   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
RIMKLA
Tdark
Family:  Enzyme
Novelty:  0.30213465
Score:  0.742
Data Source:  STRINGDB
FBLL1
Tdark
Family:  Enzyme
Novelty:  1.53294318
Score:  0.729
Data Source:  STRINGDB
LRRC46
Tdark
Novelty:  1.159245
Score:  0.682
Data Source:  STRINGDB
ADGRF2
Tdark
Family:  GPCR
Novelty:  0.35622722
Score:  0.657
Data Source:  STRINGDB
MFSD4B
Tdark
Novelty:  0.03380333
Score:  0.615
Data Source:  STRINGDB
PDZD7
Tbio
Novelty:  0.09467006
Score:  0.594
Data Source:  STRINGDB
TMEM174
Tdark
Novelty:  0.40496536
Score:  0.546
Data Source:  STRINGDB
GTF3C6
Tdark
Novelty:  1.44154731
Score:  0.545
Data Source:  STRINGDB
TRIM26
Tbio
Novelty:  0.07177119
Score:  0.531
Data Source:  STRINGDB
TMEM207
Tdark
Novelty:  0.35957705
Score:  0.511
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (791)
Items per page:
1 – 5 of 791
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
5
7
98.6
lymphocyte count
3
5
7
98.6
lymphocyte count
3
5
7
98.6
lymphocyte count
3
5
7
98.6
lymphocyte count
3
5
7
98.6
Items per page:
1 – 5 of 791
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
7
98.6
lymphocyte count
7
98.6
lymphocyte count
7
98.6
lymphocyte count
7
98.6
lymphocyte count
7
98.6
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
mitochondrial coiled-coil domain 1
715379
Dog
mitochondrial coiled-coil domain 1
VGNC:43072
607150
Cow
mitochondrial coiled-coil domain 1
VGNC:54451
617505
Opossum
mitochondrial coiled-coil domain 1
103096515
Species
Name
OMA
EggNOG
Inparanoid
Macaque
mitochondrial coiled-coil domain 1
Dog
mitochondrial coiled-coil domain 1
Cow
mitochondrial coiled-coil domain 1
Opossum
mitochondrial coiled-coil domain 1
Publication Statistics
PubMed Score 2.43
PubMed score by year
PubTator Score 1.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title