MAPK3
Mitogen-activated protein kinase 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
biological term | 1 | ||
chemical | 1 | ||
hub protein | 1 | ||
interacting protein | 1 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of NMDA receptors and postsynaptic events | ||||
Reactome | Activation of the AP-1 family of transcription factors | ||||
Reactome | Advanced glycosylation endproduct receptor signaling | ||||
Reactome | Antiviral mechanism by IFN-stimulated genes | ||||
Reactome | Apoptosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of NMDA receptors and postsynaptic events | ||||
Activation of the AP-1 family of transcription factors | ||||
Advanced glycosylation endproduct receptor signaling | ||||
Antiviral mechanism by IFN-stimulated genes | ||||
Apoptosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
appendicular lean mass | 2 | 3 | 6 | 94.7 | |||||
mean corpuscular volume | 3 | 2 | 3 | 94 | |||||
red blood cell density measurement | 2 | 1 | 2 | 87.3 | |||||
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 87 | |||||
eosinophil count | 3 | 2 | 3 | 86.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
appendicular lean mass | 6 | 94.7 | |||||
mean corpuscular volume | 3 | 94 | |||||
red blood cell density measurement | 2 | 87.3 | |||||
mean corpuscular hemoglobin concentration | 1 | 87 | |||||
eosinophil count | 3 | 86.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 3 | VGNC:8987 | 454037 | |||||
Macaque | mitogen-activated protein kinase 3 | 708938 | ||||||
Mouse | MGI:1346859 | 26417 | ||||||
Rat | RGD:3046 | 50689 | ||||||
Dog | mitogen-activated protein kinase 3 | 100855877 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 3 | |||||
Macaque | mitogen-activated protein kinase 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase 3 | |||||
PMID | Year | Title |
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