MAPK14
Mitogen-activated protein kinase 14
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
biological term | 1 | ||
chemical | 1 | ||
drug | 1 | ||
hub protein | 1 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ADP signalling through P2Y purinoceptor 1 | ||||
Reactome | Activation of PPARGC1A (PGC-1alpha) by phosphorylation | ||||
Reactome | Activation of the AP-1 family of transcription factors | ||||
Reactome | Axon guidance | ||||
Reactome | Cellular Senescence | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ADP signalling through P2Y purinoceptor 1 | ||||
Activation of PPARGC1A (PGC-1alpha) by phosphorylation | ||||
Activation of the AP-1 family of transcription factors | ||||
Axon guidance | ||||
Cellular Senescence | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 1 | 2 | 2 | 32.9 | |||||
mean corpuscular volume | 1 | 1 | 1 | 31.2 | |||||
body height | 1 | 1 | 1 | 30.2 | |||||
diabetic foot | 1 | 1 | 0 | 1.7 | 17.8 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist circumference | 2 | 32.9 | |||||
mean corpuscular volume | 1 | 31.2 | |||||
body height | 1 | 30.2 | |||||
diabetic foot | 0 | 1.7 | 17.8 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 14 | VGNC:7197 | 450161 | |||||
Macaque | mitogen-activated protein kinase 14 | 718976 | ||||||
Mouse | MGI:1346865 | 26416 | ||||||
Rat | RGD:70496 | 81649 | ||||||
Dog | mitogen-activated protein kinase 14 | VGNC:42995 | 403856 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 14 | |||||
Macaque | mitogen-activated protein kinase 14 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase 14 | |||||
PMID | Year | Title |
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