MAPK1
Mitogen-activated protein kinase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
biological term | 1 | ||
chemical | 1 | ||
hub protein | 1 | ||
interacting protein | 1 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of NMDA receptors and postsynaptic events | ||||
Reactome | Activation of the AP-1 family of transcription factors | ||||
Reactome | Advanced glycosylation endproduct receptor signaling | ||||
Reactome | Apoptosis | ||||
Reactome | Apoptotic factor-mediated response | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of NMDA receptors and postsynaptic events | ||||
Activation of the AP-1 family of transcription factors | ||||
Advanced glycosylation endproduct receptor signaling | ||||
Apoptosis | ||||
Apoptotic factor-mediated response | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 2 | 0 | 1.1 | 83.6 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 39.6 | |||||
interleukin-6 measurement | 1 | 1 | 1 | 24.5 | |||||
red blood cell density measurement | 1 | 1 | 1 | 13 | |||||
hemoglobin measurement | 1 | 1 | 1 | 10.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 83.6 | |||||
comparative body size at age 10, self-reported | 1 | 39.6 | |||||
interleukin-6 measurement | 1 | 24.5 | |||||
red blood cell density measurement | 1 | 13 | |||||
hemoglobin measurement | 1 | 10.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 1 | VGNC:12896 | 458680 | |||||
Macaque | mitogen-activated protein kinase 1 | 698569 | ||||||
Mouse | MGI:1346858 | 26413 | ||||||
Rat | RGD:70500 | 116590 | ||||||
Dog | mitogen-activated protein kinase 1 | VGNC:42991 | 477575 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 1 | |||||
Macaque | mitogen-activated protein kinase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase 1 | |||||
PMID | Year | Title |
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