You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MAP7D3
MAP7 domain-containing protein 3

Protein Summary
Description
Promotes the assembly and stability of microtubules. The protein encoded by this gene belongs to the MAP7 (microtubule-associated protein 7) family. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Mar 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316077
  • ENSP00000318086
  • ENSG00000129680
  • ENST00000370661
  • ENSP00000359695
  • ENST00000370663
  • ENSP00000359697

Symbol
  • MDP3
  • MDP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.65
cellular component
0.64
cell type or tissue
0.56
microRNA
0.56
cell line
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.75   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.75   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
CAV3
Tbio
Novelty:  0.00190092
p_int:  0.996893759
p_ni:  0.003106241
Score:  0.177
Data Source:  BioPlex,STRINGDB
TNNC2
Tbio
Novelty:  0.07759506
p_int:  0.953129831
p_ni:  0.046870169
Data Source:  BioPlex
PCDH20
Tbio
Novelty:  0.07862843
p_int:  0.93357507
p_ni:  0.06642493
Data Source:  BioPlex
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.868056948
p_ni:  0.131943052
Data Source:  BioPlex
TRAK2
Tbio
Novelty:  0.04192075
p_int:  0.861631208
p_ni:  0.138368792
Score:  0.167
Data Source:  BioPlex,STRINGDB
SPINT2
Tbio
Family:  Enzyme
Novelty:  0.0046602
p_int:  0.850782013
p_ni:  0.149217987
Data Source:  BioPlex
ATP11C
Tbio
Family:  Transporter
Novelty:  0.05441047
Score:  0.675
Data Source:  STRINGDB
DRP2
Tbio
Novelty:  0.15252692
Score:  0.658
Data Source:  STRINGDB
MAP9
Tbio
Novelty:  0.08883282
Score:  0.628
Data Source:  STRINGDB
FANCB
Tbio
Novelty:  0.00268111
Score:  0.56
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
1
1
1
37.7
pulse pressure measurement
1
1
1
32.3
systolic blood pressure
1
1
1
22.8
angina pectoris
1
1
1
21.6
educational attainment
1
1
1
6.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
1
37.7
pulse pressure measurement
1
32.3
systolic blood pressure
1
22.8
angina pectoris
1
21.6
educational attainment
1
6.1
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
MAP7 domain containing 3
712823
Mouse
MGI:2445051
320923
Rat
RGD:1565514
317614
Dog
MAP7 domain containing 3
VGNC:42990
481061
Horse
MAP7 domain containing 3
VGNC:51986
100056902
Species
Name
OMA
EggNOG
Inparanoid
Macaque
MAP7 domain containing 3
Mouse
Rat
Dog
MAP7 domain containing 3
Horse
MAP7 domain containing 3
Publication Statistics
PubMed Score 11.75
PubMed score by year
PubTator Score 9.18
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title