MAP3K21
Mitogen-activated protein kinase kinase kinase 21
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
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biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
PathwayCommons: inoh | Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) | ||||
PathwayCommons: inoh | VEGF signaling pathway ( VEGF signaling pathway ) | ||||
PathwayCommons: inoh | AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) | ||||
PathwayCommons: inoh | AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) | ||||
PathwayCommons: inoh | Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) | ||||
VEGF signaling pathway ( VEGF signaling pathway ) | ||||
AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) | ||||
AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) | ||||
Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
thyroid carcinoma | 1 | 1 | 0 | 1.3 | 47.7 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
thyroid carcinoma | 0 | 1.3 | 47.7 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase kinase kinase 21 | VGNC:53226 | 469711 | |||||
Macaque | mitogen-activated protein kinase kinase kinase 21 | 712755 | ||||||
Mouse | MGI:2385307 | 234878 | ||||||
Rat | RGD:1306091 | 307950 | ||||||
Dog | mitogen-activated protein kinase kinase kinase 21 | VGNC:52001 | 100688368 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase kinase kinase 21 | |||||
Macaque | mitogen-activated protein kinase kinase kinase 21 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase kinase kinase 21 | |||||
PMID | Year | Title |
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