Tbio MAGOHB Protein mago nashi homolog 2

Protein Summary

Description

Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway.

Uniprot Accession IDs

• Q96A72

Gene Name

• MAGOHB

Ensembl ID

• ENST00000320756
• ENSP00000319240
• ENSG00000111196

Symbol

• MAGOH2
• MGN2
• mago
• magoh

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
virus perturbation	0.76
transcription factor binding site profile	0.71
transcription factor perturbation	0.68
tissue	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.2   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 60   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.2   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0