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Tdark
MAGIX
PDZ domain-containing protein MAGIX

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.28   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.28   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
TJP1
Tbio
Novelty:  0.00040365
p_int:  0.999999755
p_ni:  2.42e-7
p_wrong:  3e-9
Score:  0.227
Data Source:  BioPlex,STRINGDB
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.999958781
p_ni:  0.000041219
Score:  0.51
Data Source:  BioPlex,STRINGDB
CDC26
Tbio
Family:  Enzyme
Novelty:  0.07456358
p_int:  0.999945374
p_ni:  0.000052591
p_wrong:  0.000002035
Score:  0.527
Data Source:  BioPlex,STRINGDB
CDC23
Tbio
Novelty:  0.0168525
p_int:  0.999922343
p_ni:  0.000077657
Score:  0.155
Data Source:  BioPlex,STRINGDB
ANAPC2
Tbio
Family:  Enzyme
Novelty:  0.19812984
p_int:  0.999898193
p_ni:  0.000101783
p_wrong:  2.4e-8
Score:  0.536
Data Source:  BioPlex,STRINGDB
CDC27
Tbio
Novelty:  0.00589846
p_int:  0.999878297
p_ni:  0.000121698
p_wrong:  5e-9
Score:  0.173
Data Source:  BioPlex,STRINGDB
ERCC1
Tbio
Novelty:  0.00079472
p_int:  0.999771367
p_ni:  0.000228384
p_wrong:  2.49e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
ANAPC1
Tbio
Family:  Enzyme
Novelty:  0.0521845
p_int:  0.999738478
p_ni:  0.000261522
Score:  0.304
Data Source:  BioPlex,STRINGDB
STK24
Tchem
Family:  Kinase
Novelty:  0.00457236
p_int:  0.999669767
p_ni:  0.000330233
Score:  0.167
Data Source:  BioPlex,STRINGDB
ANAPC4
Tbio
Family:  Enzyme
Novelty:  0.28937094
p_int:  0.999263792
p_ni:  0.00073408
p_wrong:  0.000002128
Score:  0.392
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
13.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
13.5
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 2.28
PubMed score by year
PubTator Score 3.50
PubTator score by year
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Related Publications
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PMID
Year
Title