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Tbio
MAGEH1
Melanoma-associated antigen H1

Protein Summary
Description
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000342972
  • ENSP00000343706
  • ENSG00000187601

Symbol
  • APR1
  • APR1
  • APR-1
  • MAGEH
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.8
cell type or tissue
0.62
virus perturbation
0.59
tissue sample
0.57
interacting protein
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 241.31   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 140   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 241.31   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
NGFR
Tclin
Novelty:  0.00072052
Score:  0.97
Data Source:  STRINGDB
NGF
Tchem
Novelty:  0.00008139
Score:  0.944
Data Source:  STRINGDB
SORT1
Tchem
Novelty:  0.00319862
Score:  0.941
Data Source:  STRINGDB
ATRAID
Tbio
Novelty:  0.05036748
Score:  0.79
Data Source:  STRINGDB
FAM215A
Tdark
Novelty:  0.66
Score:  0.669
Data Source:  STRINGDB
VPS11
Tbio
Novelty:  0.00496411
Score:  0.613
Data Source:  STRINGDB
RMC1
Tbio
Novelty:  0.02804116
Score:  0.573
Data Source:  STRINGDB
NSMCE4A
Tdark
Novelty:  0.45550673
Score:  0.572
Data Source:  STRINGDB
ATAD2
Tchem
Family:  Epigenetic
Novelty:  0.01103552
Score:  0.548
Data Source:  STRINGDB
MOAP1
Tbio
Novelty:  0.05070263
Score:  0.547
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
4
4
96.4
sex hormone-binding globulin measurement
4
1
4
8.7
mean corpuscular volume
1
1
1
0.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
4
96.4
sex hormone-binding globulin measurement
4
8.7
mean corpuscular volume
1
0.5
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
MAGE family member H1
VGNC:2702
107971173
Mouse
MGI:1922875
75625
Rat
RGD:1359316
367767
Dog
MAGE family member H1
VGNC:42926
491904
Horse
MAGE family member H1
VGNC:19894
100050717
Species
Name
OMA
EggNOG
Inparanoid
Chimp
MAGE family member H1
Mouse
Rat
Dog
MAGE family member H1
Horse
MAGE family member H1
Publication Statistics
PubMed Score 241.31
PubMed score by year
PubTator Score 215.07
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title