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Tbio
MAGEA10
Melanoma-associated antigen 10

Protein Summary
Description
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A, 5 (MAGEA5) gene.[provided by RefSeq, Oct 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000244096
  • ENSP00000244096
  • ENSG00000124260
  • ENST00000370323
  • ENSP00000359347

Symbol
  • MAGE10
  • CT1.10
  • MAGE10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.48
cell line
0.42
protein domain
0.41
transcription factor
0.4
disease
0.38


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.06   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 189   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.06   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (69)
NCOA2
Tbio
Novelty:  0.00510052
p_int:  1
Score:  0.422
Data Source:  BioPlex,STRINGDB
FOXJ2
Tbio
Family:  TF
Novelty:  0.02306032
p_int:  1
Score:  0.406
Data Source:  BioPlex,STRINGDB
MAGEA4
Tbio
Novelty:  0.00949096
p_int:  0.999999999
p_wrong:  1e-9
Score:  0.599
Data Source:  BioPlex,STRINGDB
FAM216A
Tdark
Novelty:  0.74863593
p_int:  0.999999999
p_ni:  1e-9
Score:  0.422
Data Source:  BioPlex,STRINGDB
MAGEA9
Tbio
Novelty:  0.07926412
p_int:  0.999999964
p_ni:  2e-8
p_wrong:  1.6e-8
Data Source:  BioPlex
KAT2A
Tchem
Family:  Epigenetic
Novelty:  0.00238831
p_int:  0.999999952
p_ni:  4.8e-8
Score:  0.257
Data Source:  BioPlex,STRINGDB
KAT2B
Tchem
Family:  Epigenetic
Novelty:  0.00172126
p_int:  0.999999937
p_ni:  6.2e-8
p_wrong:  1e-9
Score:  0.495
Data Source:  BioPlex,STRINGDB
POU2F1
Tbio
Family:  TF
Novelty:  0.00722164
p_int:  0.999999307
p_ni:  6.89e-7
p_wrong:  4e-9
Score:  0.209
Data Source:  BioPlex,STRINGDB
NRIP1
Tbio
Novelty:  0.00551568
p_int:  0.999997981
p_ni:  0.000001816
p_wrong:  2.03e-7
Score:  0.209
Data Source:  BioPlex,STRINGDB
ERI1
Tbio
Family:  Enzyme
Novelty:  0.00959105
p_int:  0.999997942
p_ni:  2e-9
p_wrong:  0.000002056
Score:  0.209
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 20.06
PubMed score by year
PubTator Score 30.56
PubTator score by year
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Related Publications
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PMID
Year
Title