Tbio MAATS1 Cilia- and flagella-associated protein 91

Protein Summary

Description

May play a role in spermatogenesis (PubMed:12223483). May regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).

Uniprot Accession IDs

• Q7Z4T9
• A0AVK2
• A8K1J9
• B3KP23
• B4DG52
• B4DZ14
• C9JUG4
• Q68DX2
• Q8TD41
• Q96A45
• Q96JE8
• CFAP91

Gene Name

• MAATS1

Ensembl ID

• ENST00000273390
• ENSP00000273390
• ENSG00000183833
• ENST00000463700
• ENSP00000419489

Symbol

• AAT1
• C3orf15
• CFAP91
• AAT1
• CFAP91
• C3orf15
• CaM-IP2
• SPATA26
• AAT1alpha

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.76
histone modification site profile	0.74
cell type or tissue	0.66
tissue sample	0.63
interacting protein	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.08   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 106   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.08   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0