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Tdark
LZIC
Protein LZIC

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377213
  • ENSP00000366418
  • ENSG00000162441
  • ENST00000377223
  • ENSP00000366430
  • ENST00000400903
  • ENSP00000383695
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.91
transcription factor binding site profile
0.83
virus perturbation
0.79
histone modification site profile
0.77
tissue
0.57


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.57   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 282   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.57   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 282   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
GINS2
Tbio
Novelty:  0.0078966
p_int:  0.999904491
p_ni:  0.000095509
p_wrong:  1e-9
Score:  0.228
Data Source:  BioPlex,STRINGDB
CCNC
Tbio
Novelty:  0.00585842
p_int:  0.999886994
p_ni:  0.000112887
p_wrong:  1.2e-7
Score:  0.663
Data Source:  BioPlex,STRINGDB
CDK8
Tchem
Family:  Kinase
Novelty:  0.00508026
p_int:  0.998654842
p_ni:  0.001345158
Score:  0.663
Data Source:  BioPlex,STRINGDB
CDK19
Tchem
Family:  Kinase
Novelty:  0.03132669
p_int:  0.996931526
p_ni:  0.003068473
p_wrong:  1e-9
Score:  0.666
Data Source:  BioPlex,STRINGDB
GINS4
Tbio
Novelty:  0.0316194
p_int:  0.995392551
p_ni:  0.004607449
Score:  0.189
Data Source:  BioPlex,STRINGDB
FSD1
Tbio
Novelty:  0.03452477
p_int:  0.983701137
p_ni:  0.007434376
p_wrong:  0.008864487
Data Source:  BioPlex
MBD5
Tbio
Family:  Epigenetic
Novelty:  0.03015349
p_int:  0.982775562
p_ni:  0.005903265
p_wrong:  0.011321172
Score:  0.189
Data Source:  BioPlex,STRINGDB
FGB
Tbio
Novelty:  0.00437751
p_int:  0.979735948
p_ni:  0.007151704
p_wrong:  0.013112349
Data Source:  BioPlex
CLSTN1
Tbio
Novelty:  0.04056624
Score:  0.63
Data Source:  STRINGDB
GPR157
Tdark
Family:  GPCR
Novelty:  0.96671087
Score:  0.63
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
leucine zipper and CTNNBIP1 domain containing
712335
Mouse
MGI:1916401
69151
Rat
RGD:1309253
366507
Dog
leucine zipper and CTNNBIP1 domain containing
VGNC:42903
100855658
Horse
leucine zipper and CTNNBIP1 domain containing
VGNC:19870
100051553
Species
Name
OMA
EggNOG
Inparanoid
Macaque
leucine zipper and CTNNBIP1 domain containing
Mouse
Rat
Dog
leucine zipper and CTNNBIP1 domain containing
Horse
leucine zipper and CTNNBIP1 domain containing
Publication Statistics
PubMed Score 3.57
PubMed score by year
PubTator Score 2.27
PubTator score by year
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Related Publications
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PMID
Year
Title