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Tbio
LYZL4
Lysozyme-like protein 4

Protein Summary
Description
May be involved in fertilization (By similarity). Has no detectable bacteriolytic and lysozyme activities in vitro (By similarity). Lysozymes (see LYZ; MIM 153450), especially C-type lysozymes, are well-recognized bacteriolytic factors widely distributed in the animal kingdom and play a mainly protective role in host defense. LYZL4 is a member of a family of lysozyme-like genes (Zhang et al., 2005 [PubMed 16014814]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287748
  • ENSP00000287748
  • ENSG00000157093
  • ENST00000441172
  • ENSP00000387897

Symbol
  • LYC4
  • LYC4
  • LYZA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
gene perturbation
0.59
PubMedID
0.58
cell type or tissue
0.45
cell line
0.43


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.78   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.78   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (14)
ANKRD27
Tbio
Novelty:  0.02843267
Score:  0.727
Data Source:  STRINGDB
YEATS4
Tbio
Novelty:  0.02632024
Score:  0.702
Data Source:  STRINGDB
ASTL
Tbio
Family:  Enzyme
Novelty:  0.02265035
Score:  0.701
Data Source:  STRINGDB
SPRYD4
Tdark
Novelty:  0.44404169
Score:  0.654
Data Source:  STRINGDB
NAGS
Tbio
Family:  Enzyme
Novelty:  0.0051524
Score:  0.647
Data Source:  STRINGDB
EGFLAM
Tbio
Novelty:  0.02955802
Score:  0.628
Data Source:  STRINGDB
MIP
Tbio
Novelty:  0.00299543
Score:  0.551
Data Source:  STRINGDB
CLEC3A
Tdark
Novelty:  0.21498836
Score:  0.542
Data Source:  STRINGDB
C12orf71
Tdark
Novelty:  6.74822415
Score:  0.533
Data Source:  STRINGDB
CLEC2B
Tbio
Novelty:  0.06581244
Score:  0.532
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
6
6
8
87.6
comparative body size at age 10, self-reported
1
1
1
56.6
physical activity measurement
1
2
2
28.1
body height
1
1
1
11.7
visceral adipose tissue measurement
1
1
1
4.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
8
87.6
comparative body size at age 10, self-reported
1
56.6
physical activity measurement
2
28.1
body height
1
11.7
visceral adipose tissue measurement
1
4.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
lysozyme like 4
VGNC:6360
470801
Macaque
lysozyme like 4
716549
Mouse
MGI:1916282
69032
Rat
RGD:1308401
363168
Dog
lysozyme like 4
VGNC:42902
100855480
Species
Name
OMA
EggNOG
Inparanoid
Chimp
lysozyme like 4
Macaque
lysozyme like 4
Mouse
Rat
Dog
lysozyme like 4
Publication Statistics
PubMed Score 7.78
PubMed score by year
PubTator Score 7.42
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title