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Tdark
LYSMD3
LysM and putative peptidoglycan-binding domain-containing protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315948
  • ENSP00000314518
  • ENSG00000176018
  • ENST00000500869
  • ENSP00000427020
  • ENST00000509384
  • ENSP00000427683
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.89
histone modification site profile
0.87
transcription factor binding site profile
0.83
tissue
0.61
transcription factor perturbation
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.86   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.86   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
ARL6IP1
Tbio
Novelty:  0.07644032
Score:  0.761
Data Source:  STRINGDB
ARRDC3
Tbio
Novelty:  0.04840692
Score:  0.731
Data Source:  STRINGDB
MBLAC2
Tdark
Family:  Enzyme
Novelty:  0.47407992
Score:  0.7
Data Source:  STRINGDB
ADGRV1
Tbio
Family:  GPCR
Novelty:  0.01398129
Score:  0.644
Data Source:  STRINGDB
WSCD1
Tdark
Novelty:  0.70877323
Score:  0.581
Data Source:  STRINGDB
POLR3G
Tbio
Family:  Enzyme
Novelty:  0.04923071
Score:  0.557
Data Source:  STRINGDB
MYCBPAP
Tbio
Novelty:  1.11929455
Score:  0.539
Data Source:  STRINGDB
ACOT9
Tbio
Family:  Enzyme
Novelty:  0.17405187
Score:  0.514
Data Source:  STRINGDB
CFAP161
Tdark
Novelty:  1.37101386
Score:  0.505
Data Source:  STRINGDB
SMG1
Tchem
Family:  Kinase
Novelty:  0.00854339
Score:  0.495
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
83.2
methionine measurement
1
1
0
7.6
75.2
triglyceride measurement
4
1
4
56.1
brain measurement
1
1
0
7.7
51.6
blood urea nitrogen measurement
1
1
1
45.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
83.2
methionine measurement
0
7.6
75.2
triglyceride measurement
4
56.1
brain measurement
0
7.7
51.6
blood urea nitrogen measurement
1
45.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
LysM domain containing 3
VGNC:6943
461758
Macaque
LysM domain containing 3
697655
Mouse
MGI:1915906
80289
Rat
RGD:1308805
315923
Dog
LysM domain containing 3
VGNC:42897
488913
Species
Name
OMA
EggNOG
Inparanoid
Chimp
LysM domain containing 3
Macaque
LysM domain containing 3
Mouse
Rat
Dog
LysM domain containing 3
Publication Statistics
PubMed Score 1.86
PubMed score by year
PubTator Score 0.99
PubTator score by year
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Related Publications
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PMID
Year
Title