You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
LYRM2
LYR motif-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000523377
  • ENSP00000430025
  • ENSG00000083099

Symbol
  • DJ122O8.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
disease perturbation
0.87
virus perturbation
0.85
microRNA
0.74
transcription factor perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
NDUFAB1
Tclin
Novelty:  0.00190242
p_int:  1
Score:  0.877
Data Source:  BioPlex,STRINGDB
OXSM
Tbio
Family:  Enzyme
Novelty:  0.00615894
p_int:  0.999945202
p_ni:  0.000054794
p_wrong:  4e-9
Score:  0.869
Data Source:  BioPlex,STRINGDB
YARS2
Tbio
Family:  Enzyme
Novelty:  0.00522139
p_int:  0.999836313
p_ni:  0.000163686
p_wrong:  1e-9
Score:  0.168
Data Source:  BioPlex,STRINGDB
ACADS
Tbio
Family:  Enzyme
Novelty:  0.00841051
p_int:  0.949449933
p_ni:  0.050550067
Score:  0.19
Data Source:  BioPlex,STRINGDB
ETFRF1
Tdark
Novelty:  1.28847105
Score:  0.803
Data Source:  STRINGDB
SDHAF3
Tbio
Family:  Enzyme
Novelty:  0.01155522
Score:  0.802
Data Source:  STRINGDB
LYRM1
Tbio
Novelty:  0.11803722
Score:  0.743
Data Source:  STRINGDB
LYRM4
Tbio
Novelty:  0.03319832
Score:  0.716
Data Source:  STRINGDB
LYRM9
Tdark
Novelty:  0.73237725
Score:  0.701
Data Source:  STRINGDB
LYRM7
Tbio
Novelty:  0.16270565
Score:  0.637
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
2
2
45.6
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
45.6
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
LYR motif containing 2
701575
Mouse
MGI:1917573
108755
Rat
RGD:1597334
690354
Dog
LYR motif containing 2
VGNC:42894
481920
Horse
LYR motif containing 2
VGNC:19860
100065742
Species
Name
OMA
EggNOG
Inparanoid
Macaque
LYR motif containing 2
Mouse
Rat
Dog
LYR motif containing 2
Horse
LYR motif containing 2
Publication Statistics
PubMed Score 3.29
PubMed score by year
PubTator Score 1.00
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title