LYPLA2
Acyl-protein thioesterase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
interacting protein | 0.76 | ||
metabolite | 0.75 | ||
histone modification site profile | 0.72 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | L1CAM interactions | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Developmental Biology | ||||
L1CAM interactions | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte count | 6 | 4 | 6 | 92.4 | |||||
eosinophil count | 3 | 3 | 3 | 91.9 | |||||
reticulocyte measurement | 3 | 2 | 3 | 90.5 | |||||
eosinophil percentage of leukocytes | 2 | 2 | 2 | 85.5 | |||||
eosinophil percentage of granulocytes | 1 | 1 | 1 | 35 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte count | 6 | 92.4 | |||||
eosinophil count | 3 | 91.9 | |||||
reticulocyte measurement | 3 | 90.5 | |||||
eosinophil percentage of leukocytes | 2 | 85.5 | |||||
eosinophil percentage of granulocytes | 1 | 35 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | lysophospholipase II | 719074 | ||||||
Mouse | MGI:1347000 | 26394 | ||||||
Rat | RGD:620210 | 83510 | ||||||
Dog | lysophospholipase II | VGNC:42891 | 100855579 | |||||
Horse | lysophospholipase II | VGNC:19857 | 100071559 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | lysophospholipase II | |||||
Mouse | ||||||
Rat | ||||||
Dog | lysophospholipase II | |||||
Horse | lysophospholipase II | |||||
PMID | Year | Title |
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