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Tbio
LYPD4
Ly6/PLAUR domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000343055
  • ENSP00000339568
  • ENSG00000273111
  • ENST00000601246
  • ENSP00000472570
  • ENST00000609812
  • ENSP00000476510

Symbol
  • SMR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.53
tissue
0.52
cell type or tissue
0.41
chemical
0.41
gene perturbation
0.34


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 254.7   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 254.7   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (153)
CBWD3
Tdark
Novelty:  0.03639787
p_int:  0.999967415
p_ni:  0.000032585
Score:  0.184
Data Source:  BioPlex,STRINGDB
NPTX2
Tbio
Novelty:  0.00686292
p_int:  0.999779561
p_ni:  0.000192625
p_wrong:  0.000027814
Data Source:  BioPlex
OBSCN
Tbio
Family:  Kinase
Novelty:  0.01173699
p_int:  0.999716094
p_ni:  0.000275138
p_wrong:  0.000008769
Score:  0.169
Data Source:  BioPlex,STRINGDB
FBXL18
Tdark
Novelty:  0.33137957
p_int:  0.99776622
p_ni:  0.002165208
p_wrong:  0.000068572
Data Source:  BioPlex
FAM198A
Tdark
Novelty:  0.65293749
p_int:  0.997374177
p_ni:  0.002586533
p_wrong:  0.000039291
Data Source:  BioPlex
NPTX1
Tbio
Novelty:  0.02872516
p_int:  0.993743615
p_ni:  0.006256367
p_wrong:  1.8e-8
Data Source:  BioPlex
ERN1
Tchem
Family:  Kinase
Novelty:  0.00141922
p_int:  0.992060261
p_ni:  0.007915067
p_wrong:  0.000024672
Data Source:  BioPlex
GDF11
Tclin
Novelty:  0.00585981
p_int:  0.990503232
p_ni:  0.009279198
p_wrong:  0.000217569
Data Source:  BioPlex
FUT11
Tbio
Family:  Enzyme
Novelty:  0.16098097
p_int:  0.990383687
p_ni:  0.009600619
p_wrong:  0.000015695
Data Source:  BioPlex
PRR14
Tbio
Novelty:  0.22401806
p_int:  0.990307645
p_ni:  0.000262368
p_wrong:  0.009429988
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of proteins (R-HSA-392499)

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Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational modification: synthesis of GPI-anchored proteins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational modification: synthesis of GPI-anchored proteins
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum carcinoembryonic antigen measurement
1
1
1
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum carcinoembryonic antigen measurement
1
38.8
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
LY6/PLAUR domain containing 4
706070
Mouse
MGI:2687054
232973
Rat
RGD:6498582
100910410
Dog
LY6/PLAUR domain containing 4
VGNC:42886
100688665
Horse
LY6/PLAUR domain containing 4
VGNC:19854
100069898
Species
Name
OMA
EggNOG
Inparanoid
Macaque
LY6/PLAUR domain containing 4
Mouse
Rat
Dog
LY6/PLAUR domain containing 4
Horse
LY6/PLAUR domain containing 4
Publication Statistics
PubMed Score 254.70
PubMed score by year
PubTator Score 722.71
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title