Tbio LYPD3 Ly6/PLAUR domain-containing protein 3

Protein Summary

Description

Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

Uniprot Accession IDs

• O95274
• Q9UJ74

Gene Name

• LYPD3

Ensembl ID

• ENST00000244333
• ENSP00000244333
• ENSG00000124466

Symbol

• C4.4A
• C4.4A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.9
disease perturbation	0.62
tissue sample	0.62
small molecule perturbation	0.55
cellular component	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.31   (req: < 5)

Gene RIFs: 16   (req: <= 3)

Antibodies: 235   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.31   (req: >= 5)

Gene RIFs: 16   (req: > 3)

Antibodies: 235   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0