You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
LYG2
Lysozyme g-like protein 2

Protein Summary
Description
May act as a potent antibacterial protein that may play a role in the innate immunity. The protein encoded by this gene contains a SLT domain, a protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryotic lysozymes (GEWL). SLT domain catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyglucosamine (GlcNAc). [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333017
  • ENSP00000327533
  • ENSG00000185674
  • ENST00000409238
  • ENSP00000386939
  • ENST00000423800
  • ENSP00000390357
  • ENST00000626374
  • ENSP00000487012

Symbol
  • LYGH
  • LYGH
  • LYSG2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.68
cell type or tissue
0.54
tissue
0.45
protein domain
0.41
transcription factor
0.39


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.03   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.03   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (62)
NID2
Tbio
Novelty:  0.01638372
p_int:  0.999999806
p_ni:  1.94e-7
Data Source:  BioPlex
SPATA20
Tdark
Novelty:  0.34126403
p_int:  0.999996953
p_ni:  0.000003047
Data Source:  BioPlex
IL31RA
Tbio
Novelty:  0.00737445
p_int:  0.999984153
p_ni:  0.000015847
Data Source:  BioPlex
FBXL4
Tbio
Novelty:  0.04286856
p_int:  0.999981311
p_ni:  0.000018689
Data Source:  BioPlex
RAB11B
Tbio
Family:  Enzyme
Novelty:  0.00557558
p_int:  0.999955958
p_ni:  0.000044042
Data Source:  BioPlex
VPS33B
Tbio
Novelty:  0.02221093
p_int:  0.999773776
p_ni:  0.000226199
p_wrong:  2.5e-8
Data Source:  BioPlex
VIPAS39
Tbio
Novelty:  0.02348642
p_int:  0.999441262
p_ni:  0.000210236
p_wrong:  0.000348503
Score:  0.169
Data Source:  BioPlex,STRINGDB
PYHIN1
Tbio
Novelty:  0.06662677
p_int:  0.998912578
p_ni:  0.00108742
p_wrong:  2e-9
Score:  0.158
Data Source:  BioPlex,STRINGDB
SGO2
Tbio
Novelty:  0.05544423
p_int:  0.998851984
p_ni:  0.001148016
Data Source:  BioPlex
NSMAF
Tbio
Novelty:  0.08595515
p_int:  0.998757442
p_ni:  0.001242554
p_wrong:  3e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
2
2
3
81.6
reticulocyte count
2
2
3
80
heel bone mineral density
2
2
2
54.4
lifestyle measurement
1
1
1
27.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
3
81.6
reticulocyte count
3
80
heel bone mineral density
2
54.4
lifestyle measurement
1
27.3
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
lysozyme g2
VGNC:48975
470449
Macaque
lysozyme g2
713778
Mouse
MGI:2685622
332427
Rat
Dog
lysozyme g2
VGNC:42881
481338
Species
Name
OMA
EggNOG
Inparanoid
Chimp
lysozyme g2
Macaque
lysozyme g2
Mouse
Rat
Dog
lysozyme g2
Publication Statistics
PubMed Score 8.03
PubMed score by year
PubTator Score 3.11
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title