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Tbio
LY6G6D
Lymphocyte antigen 6 complex locus protein G6d

Protein Summary
Description
LY6G6D belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375825
  • ENSP00000364985
  • ENSG00000244355
  • ENST00000400080
  • ENSP00000382952
  • ENSG00000206402
  • ENST00000419389
  • ENSP00000389619
  • ENSG00000226603
  • ENST00000420378
  • ENSP00000397576
  • ENSG00000234443
  • ENST00000434515
  • ENSP00000392651
  • ENSG00000235302
  • ENST00000440095
  • ENSP00000390777
  • ENSG00000225993
  • ENST00000444880
  • ENSP00000395722
  • ENSG00000236902

Symbol
  • C6orf23
  • G6D
  • MEGT1
  • NG25
  • G6D
  • NG25
  • LY6-D
  • MEGT1
  • C6orf23
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.72
PubMedID
0.6
cell type or tissue
0.54
cell line
0.45
phenotype
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.89   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 99   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.89   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0