LY6G6C
Lymphocyte antigen 6 complex locus protein G6c
Protein Summary
LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]
- ENST00000375819
- ENSP00000364978
- ENSG00000204421
- ENST00000383413
- ENSP00000372905
- ENSG00000206398
- ENST00000419939
- ENSP00000388591
- ENSG00000235452
- ENST00000428121
- ENSP00000411365
- ENSG00000228250
- ENST00000428498
- ENSP00000410398
- ENSG00000228859
- ENST00000434915
- ENSP00000415732
- ENSG00000236183
- ENST00000448386
- ENSP00000409428
- ENSG00000235925
- C6orf24
- G6C
- NG24
- G6c
- NG24
- C6orf24
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
small molecule perturbation | 0.69 | ||
disease perturbation | 0.68 | ||
tissue | 0.56 | ||
transcription factor perturbation | 0.54 | ||
disease | 0.51 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.47 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 89 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.47 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 89 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0