LY6E
Lymphocyte antigen 6E
Protein Summary
Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response.
- ENST00000292494
- ENSP00000292494
- ENSG00000160932
- ENST00000429120
- ENSP00000414307
- ENST00000520466
- ENSP00000428572
- ENST00000521003
- ENSP00000428169
- ENST00000521699
- ENSP00000427915
- ENST00000522024
- ENSP00000428442
- ENST00000522971
- ENSP00000428159
- ENST00000619718
- ENSP00000482517
- ENSG00000278032
- ENST00000631568
- ENSP00000488891
- ENST00000632424
- ENSP00000488421
- ENST00000632516
- ENSP00000487664
- ENST00000632519
- ENSP00000488443
- ENST00000632812
- ENSP00000488556
- ENST00000633451
- ENSP00000488559
- 9804
- RIGE
- SCA2
- TSA1
- RIGE
- SCA2
- RIG-E
- SCA-2
- TSA-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.96 | ||
PubMedID | 0.92 | ||
transcription factor perturbation | 0.91 | ||
gene perturbation | 0.84 | ||
kinase perturbation | 0.81 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 167.26 (req: < 5)
Gene RIFs: 17 (req: <= 3)
Antibodies: 186 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 167.26 (req: >= 5)
Gene RIFs: 17 (req: > 3)
Antibodies: 186 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0