Tbio LY6D Lymphocyte antigen 6D

Protein Summary

Description

May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification.

Uniprot Accession IDs

• Q14210
• B2R5F1
• D3DWJ0
• O43783
• Q6GTV9
• Q8TBD4
• Q92933
• Ly-6D

Gene Name

• LY6D

Ensembl ID

• ENST00000301263
• ENSP00000301263
• ENSG00000167656

Symbol

• E48
• E48
• Ly-6D

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.96
kinase perturbation	0.81
small molecule perturbation	0.61
cell type or tissue	0.52
cell line	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.29   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.29   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0