Tbio LUZP1 Leucine zipper protein 1

Protein Summary

Description

This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Uniprot Accession IDs

• Q86V48
• Q5TH93
• Q8N4X3
• Q8TEH1

Gene Name

• LUZP1

Ensembl ID

• ENST00000302291
• ENSP00000303758
• ENSG00000169641
• ENST00000314174
• ENSP00000313705
• ENST00000418342
• ENSP00000393460

Symbol

• LUZP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
ligand (protein) perturbation	0.96
microRNA	0.93
interacting protein	0.82
transcription factor perturbation	0.8
disease perturbation	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.87   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 101   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.87   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0