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Tdark
LURAP1L
Leucine rich adaptor protein 1-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319264
  • ENSP00000321026
  • ENSG00000153714

Symbol
  • C9orf150
  • LRAP35b
  • bA3L8.2
  • C9orf150
  • HYST0841
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.76
PubMedID
0.71
transcription factor
0.71
cellular component
0.68
cell line
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (34)
CDC42BPA
Tchem
Family:  Kinase
Novelty:  0.02575412
p_int:  0.999999926
p_ni:  7.4e-8
Score:  0.282
Data Source:  BioPlex,STRINGDB
CDC42BPB
Tchem
Family:  Kinase
Novelty:  0.12012285
p_int:  0.999999622
p_ni:  3.78e-7
Score:  0.274
Data Source:  BioPlex,STRINGDB
SHTN1
Tbio
Novelty:  0.06452923
p_int:  0.999996307
p_ni:  0.000003689
p_wrong:  4e-9
Score:  0.516
Data Source:  BioPlex,STRINGDB
FBXO28
Tbio
Novelty:  0.10548865
p_int:  0.999974142
p_ni:  0.000025858
Data Source:  BioPlex
HSF1
Tchem
Family:  TF
Novelty:  0.00450276
p_int:  0.999925924
p_ni:  0.000073776
p_wrong:  3.01e-7
Score:  0.28
Data Source:  BioPlex,STRINGDB
NEFM
Tbio
Novelty:  0.00239134
p_int:  0.999717334
p_ni:  0.000282666
Score:  0.211
Data Source:  BioPlex,STRINGDB
SNTB2
Tbio
Novelty:  0.05469501
p_int:  0.995330484
p_ni:  0.00465732
p_wrong:  0.000012196
Score:  0.226
Data Source:  BioPlex,STRINGDB
SLC4A3
Tbio
Family:  Transporter
Novelty:  0.04796224
Score:  0.575
Data Source:  STRINGDB
RPS23
Tbio
Novelty:  0.01846154
Score:  0.575
Data Source:  STRINGDB
ERICH5
Tdark
Novelty:  5.57504212
Score:  0.546
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
1
1
0
1.2
86.6
hair colour measurement
1
1
1
86
suntan
1
1
1
68.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hair color
0
1.2
86.6
hair colour measurement
1
86
suntan
1
68.8
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leucine rich adaptor protein 1 like
VGNC:8905
738685
Macaque
leucine rich adaptor protein 1 like
714595
Mouse
MGI:106510
52829
Rat
RGD:1308059
362535
Dog
leucine rich adaptor protein 1 like
VGNC:42867
610949
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leucine rich adaptor protein 1 like
Macaque
leucine rich adaptor protein 1 like
Mouse
Rat
Dog
leucine rich adaptor protein 1 like
Publication Statistics
PubMed Score 1.33
PubMed score by year
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Related Publications
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PMID
Year
Title