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Tchem
LTB4R2
Leukotriene B4 receptor 2

Protein Summary
Description
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000528054
  • ENSP00000432146
  • ENSG00000213906
  • ENST00000533293
  • ENSP00000433290
  • ENST00000543919
  • ENSP00000445772
  • ENST00000643080
  • ENSP00000494694
  • ENSG00000285203
  • ENST00000644309
  • ENSP00000494877
  • ENST00000645084
  • ENSP00000496382

Symbol
  • BLT2R
  • BLTR2
  • BLT2
  • NOP9
  • BLTR2
  • JULF2
  • KPG_004
  • LTB4-R2
  • LTB4-R 2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.63
protein domain
0.58
cell line
0.55
tissue sample
0.54
biological process
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 118.08   (req: < 5)
Gene RIFs: 50   (req: <= 3)
Antibodies: 213   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 118.08   (req: >= 5)
Gene RIFs: 50   (req: > 3)
Antibodies: 213   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 26
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0