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Tbio
LRRN1
Leucine-rich repeat neuronal protein 1

Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.87   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.87   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (48)
PTPRD
Tbio
Family:  Enzyme
Novelty:  0.01059407
p_int:  0.994830991
p_ni:  0.005164879
p_wrong:  0.00000413
Score:  0.396
Data Source:  BioPlex,STRINGDB
GHITM
Tbio
Novelty:  0.00360652
p_int:  0.989863145
p_ni:  0.010136855
Data Source:  BioPlex
ST7
Tbio
Novelty:  0.0339662
p_int:  0.762536241
p_ni:  0.237463743
p_wrong:  1.5e-8
Score:  0.235
Data Source:  BioPlex,STRINGDB
LRRC2
Tdark
Novelty:  0.51684076
Score:  0.7
Data Source:  STRINGDB
LRRC1
Tbio
Novelty:  0.08141846
Score:  0.692
Data Source:  STRINGDB
LRR1
Tbio
Novelty:  0.02407468
Score:  0.689
Data Source:  STRINGDB
ADGRL3
Tbio
Family:  GPCR
Novelty:  0.00268343
Score:  0.685
Data Source:  STRINGDB
ADGRL1
Tbio
Family:  GPCR
Novelty:  0.00957739
Score:  0.685
Data Source:  STRINGDB
ADGRL2
Tbio
Family:  GPCR
Novelty:  0.00985539
Score:  0.685
Data Source:  STRINGDB
UFC1
Tbio
Novelty:  0.04181639
Score:  0.672
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
3
2
5
60.1
self reported educational attainment
1
1
1
28.1
risk-taking behaviour
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
5
60.1
self reported educational attainment
1
28.1
risk-taking behaviour
1
24.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat neuronal 1
VGNC:13006
470736
Macaque
leucine rich repeat neuronal 1
703993
Mouse
MGI:106038
16979
Rat
RGD:1564145
500280
Dog
leucine rich repeat neuronal 1
VGNC:42824
484682
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat neuronal 1
Macaque
leucine rich repeat neuronal 1
Mouse
Rat
Dog
leucine rich repeat neuronal 1
Publication Statistics
PubMed Score 12.87
PubMed score by year
PubTator Score 5.27
PubTator score by year
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Related Publications
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PMID
Year
Title