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Tdark
LRRC47
Leucine-rich repeat-containing protein 47

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378251
  • ENSP00000367498
  • ENSG00000130764

Symbol
  • KIAA1185
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.99
kinase perturbation
0.91
histone modification site profile
0.75
transcription factor binding site profile
0.66
tissue sample
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.15   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.15   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (125)
EIF1AD
Tdark
Novelty:  0.23915521
p_int:  0.99161944
p_ni:  0.00838056
Data Source:  BioPlex
POLE3
Tbio
Family:  Enzyme
Novelty:  0.09657513
p_int:  0.824218868
p_ni:  0.175781132
Data Source:  BioPlex
EPRS
Tchem
Family:  Enzyme
Novelty:  0.00084896
Score:  0.972
Data Source:  STRINGDB
FARSA
Tbio
Family:  Enzyme
Novelty:  0.03623677
Score:  0.966
Data Source:  STRINGDB
YARS
Tchem
Family:  Enzyme
Novelty:  0.00302115
Score:  0.924
Data Source:  STRINGDB
EIF2A
Tbio
Novelty:  0.08652858
Score:  0.882
Data Source:  STRINGDB
BBS10
Tbio
Novelty:  0.03343798
Score:  0.841
Data Source:  STRINGDB
WARS
Tbio
Family:  Enzyme
Novelty:  0.00202764
Score:  0.823
Data Source:  STRINGDB
FARS2
Tchem
Family:  Enzyme
Novelty:  0.00771459
Score:  0.803
Data Source:  STRINGDB
FDXACB1
Tdark
Novelty:  67
Score:  0.803
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
3
7
96.6
reticulocyte count
7
2
9
94.7
reticulocyte measurement
3
2
5
94.3
hemoglobin measurement
3
2
3
91.9
mean corpuscular volume
1
1
1
86.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
7
96.6
reticulocyte count
9
94.7
reticulocyte measurement
5
94.3
hemoglobin measurement
3
91.9
mean corpuscular volume
1
86.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat containing 47
VGNC:1305
457237
Macaque
leucine rich repeat containing 47
695608
Mouse
MGI:1920196
72946
Rat
RGD:1308599
362672
Dog
leucine rich repeat containing 47
VGNC:42801
489622
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat containing 47
Macaque
leucine rich repeat containing 47
Mouse
Rat
Dog
leucine rich repeat containing 47
Publication Statistics
PubMed Score 1.15
PubMed score by year
PubTator Score 0.17
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title