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Tdark
LRRC20
Leucine-rich repeat-containing protein 20

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355790
  • ENSP00000348043
  • ENSG00000172731
  • ENST00000357631
  • ENSP00000350255
  • ENST00000358141
  • ENSP00000350860
  • ENST00000373224
  • ENSP00000362321
  • ENST00000395011
  • ENSP00000378458
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.76
transcription factor binding site profile
0.68
cellular component
0.67
small molecule perturbation
0.67
tissue sample
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.51   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
POTEI
Tdark
Novelty:  0.41311202
p_int:  0.999999679
p_ni:  3.21e-7
Data Source:  BioPlex
ACTA2
Tbio
Novelty:  0.00199354
p_int:  0.999942079
p_ni:  0.000057921
Data Source:  BioPlex
ACTB
Tbio
Novelty:  0.00006048
p_int:  0.999578029
p_ni:  0.000421971
Data Source:  BioPlex
ACTBL2
Tbio
Novelty:  0.18080702
p_int:  0.991112102
p_ni:  0.000870899
p_wrong:  0.008016999
Score:  0.236
Data Source:  BioPlex,STRINGDB
SUGT1
Tbio
Novelty:  0.1042721
p_int:  0.976635036
p_ni:  0.023364965
Data Source:  BioPlex
LRRC31
Tdark
Novelty:  0.46385091
Score:  0.715
Data Source:  STRINGDB
ADGRL1
Tbio
Family:  GPCR
Novelty:  0.00957739
Score:  0.683
Data Source:  STRINGDB
ADGRL2
Tbio
Family:  GPCR
Novelty:  0.00985539
Score:  0.683
Data Source:  STRINGDB
ADGRL3
Tbio
Family:  GPCR
Novelty:  0.00268343
Score:  0.683
Data Source:  STRINGDB
PRRG2
Tbio
Novelty:  0.16164794
Score:  0.679
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
1
1
1
40.8
IGF-1 measurement
1
1
1
25.8
comparative body size at age 10, self-reported
1
1
1
23.7
inorganic pyrophosphatase measurement
1
1
1
20
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
1
40.8
IGF-1 measurement
1
25.8
comparative body size at age 10, self-reported
1
23.7
inorganic pyrophosphatase measurement
1
20
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat containing 20
VGNC:9758
747057
Macaque
leucine rich repeat containing 20
710594
Mouse
MGI:2387182
216011
Rat
RGD:1566140
499430
Dog
leucine rich repeat containing 20
VGNC:42789
609579
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leucine rich repeat containing 20
Macaque
leucine rich repeat containing 20
Mouse
Rat
Dog
leucine rich repeat containing 20
Publication Statistics
PubMed Score 0.51
PubMed score by year
PubTator Score 0.14
PubTator score by year
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Related Publications
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PMID
Year
Title