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Tbio
LRRC15
Leucine-rich repeat-containing protein 15

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000347624
  • ENSP00000306276
  • ENSG00000172061
  • ENST00000428839
  • ENSP00000413707

Symbol
  • LIB
  • LIB
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.81
virus perturbation
0.76
protein domain
0.73
interacting protein
0.72
cell line
0.67


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.52   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.52   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (78)
GDF5
Tbio
Novelty:  0.00218118
p_int:  0.999969635
p_ni:  0.000030365
Score:  0.231
Data Source:  BioPlex,STRINGDB
CLEC11A
Tbio
Novelty:  0.03060601
p_int:  0.999957403
p_ni:  0.000041625
p_wrong:  9.73e-7
Data Source:  BioPlex
C1GALT1
Tbio
Family:  Enzyme
Novelty:  0.01191596
p_int:  0.999912938
p_ni:  0.000086828
p_wrong:  2.35e-7
Data Source:  BioPlex
RAB40AL
Tbio
Novelty:  0.00908832
p_int:  0.999705123
p_ni:  0.000294877
Data Source:  BioPlex
MACROD1
Tchem
Family:  Enzyme
Novelty:  0.03610474
p_int:  0.99923279
p_ni:  0.000308986
p_wrong:  0.000458223
Data Source:  BioPlex
IL31RA
Tbio
Novelty:  0.00737445
p_int:  0.999181863
p_ni:  0.000818137
Data Source:  BioPlex
FBXL4
Tbio
Novelty:  0.04286856
p_int:  0.999093565
p_ni:  0.000906427
p_wrong:  8e-9
Data Source:  BioPlex
OR51E2
Tchem
Family:  oGPCR
Novelty:  0.02435259
p_int:  0.998552786
p_ni:  0.001447214
Data Source:  BioPlex
RAB11B
Tbio
Family:  Enzyme
Novelty:  0.00557558
p_int:  0.9978585
p_ni:  0.0021415
Score:  0.197
Data Source:  BioPlex,STRINGDB
FMOD
Tbio
Novelty:  0.00459438
p_int:  0.997491361
p_ni:  0.000071558
p_wrong:  0.002437081
Score:  0.373
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
7
6
8
91.9
TNF-related activation-induced cytokine measurement
1
1
1
63.8
interleukin-27 measurement
1
1
1
61.6
platelet count
2
2
2
48.5
gut microbiome measurement
1
1
1
27.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
8
91.9
TNF-related activation-induced cytokine measurement
1
63.8
interleukin-27 measurement
1
61.6
platelet count
2
48.5
gut microbiome measurement
1
27.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
leucine rich repeat containing 15
707574
Mouse
MGI:1921738
74488
Rat
RGD:70551
246296
Dog
leucine rich repeat containing 15
VGNC:42786
488041
Horse
leucine rich repeat containing 15
VGNC:19769
100069043
Species
Name
OMA
EggNOG
Inparanoid
Macaque
leucine rich repeat containing 15
Mouse
Rat
Dog
leucine rich repeat containing 15
Horse
leucine rich repeat containing 15
Publication Statistics
PubMed Score 47.52
PubMed score by year
PubTator Score 29.62
PubTator score by year
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Related Publications
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PMID
Year
Title