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Tdark
LRP11
Low-density lipoprotein receptor-related protein 11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000239367
  • ENSP00000239367
  • ENSG00000120256

Symbol
  • MANSC3
  • bA350J20.3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
protein domain
0.85
transcription factor binding site profile
0.74
histone modification site profile
0.65
gene perturbation
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.52   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.52   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (42)
FAM19A3
Tdark
Novelty:  0.37183557
p_int:  0.986950295
p_ni:  0.013049705
Data Source:  BioPlex
PSCA
Tbio
Novelty:  0.00323778
p_int:  0.973711177
p_ni:  0.026288783
p_wrong:  4e-8
Data Source:  BioPlex
CD1B
Tbio
Novelty:  0.00102701
p_int:  0.96222109
p_ni:  0.037778909
Data Source:  BioPlex
SRPRB
Tbio
Novelty:  0.04735362
p_int:  0.96222109
p_ni:  0.037778909
Data Source:  BioPlex
LYZL2
Tdark
Family:  Enzyme
Novelty:  0.50542161
p_int:  0.958575442
p_ni:  0.041424545
p_wrong:  1.3e-8
Data Source:  BioPlex
LRRTM1
Tbio
Novelty:  0.0409182
p_int:  0.952610203
p_ni:  0.047389797
Data Source:  BioPlex
PLA2G10
Tchem
Family:  Enzyme
Novelty:  0.00289317
p_int:  0.931081117
p_ni:  0.068918883
Data Source:  BioPlex
GINM1
Tdark
Novelty:  1.0701107
p_int:  0.92679903
p_ni:  0.07320097
Data Source:  BioPlex
LY86
Tbio
Novelty:  0.00314575
p_int:  0.925543772
p_ni:  0.074456227
p_wrong:  1e-9
Data Source:  BioPlex
SPCS3
Tbio
Family:  Enzyme
Novelty:  0.13677259
p_int:  0.884523443
p_ni:  0.115476522
p_wrong:  3.5e-8
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
LDL receptor related protein 11
VGNC:3370
463063
Macaque
LDL receptor related protein 11
697652
Mouse
MGI:2442989
237253
Dog
LDL receptor related protein 11
VGNC:42773
100688818
Cow
LDL receptor related protein 11
VGNC:30988
617450
Species
Name
OMA
EggNOG
Inparanoid
Chimp
LDL receptor related protein 11
Macaque
LDL receptor related protein 11
Mouse
Dog
LDL receptor related protein 11
Cow
LDL receptor related protein 11
Publication Statistics
PubMed Score 4.52
PubMed score by year
PubTator Score 2.43
PubTator score by year
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Related Publications
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PMID
Year
Title