LONRF3
LON peptidase N-terminal domain and RING finger protein 3
Protein Summary
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Multiple alternatively spliced transcript variants have been suggested, but their full length natures are not clear. [provided by RefSeq, Jul 2008]
- ENST00000304778
- ENSP00000307732
- ENSG00000175556
- ENST00000371628
- ENSP00000360690
- ENST00000481285
- ENSP00000435426
- RNF127
- RNF127
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.99 | ||
transcription factor perturbation | 0.91 | ||
PubMedID | 0.72 | ||
molecular function | 0.67 | ||
gene perturbation | 0.65 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.65 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 126 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.65 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 126 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (69)
AGO3
Novelty: 0.01664154
p_int: 0.999997875
p_ni: 0.000001926
p_wrong: 1.99e-7
Score: 0.324
Data Source: BioPlex,STRINGDB
DMD
Novelty: 0.00025661
p_int: 0.999980955
p_ni: 2.75e-7
p_wrong: 0.00001877
Score: 0.259
Data Source: BioPlex,STRINGDB
RFPL4B
Novelty: 2.42779597
p_int: 0.999884541
p_ni: 0.000004155
p_wrong: 0.000111304
Score: 0.179
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (1)
Functions (1)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | LON peptidase N-terminal domain and ring finger 3 | VGNC:1366 | 473758 | |||||
Macaque | LON peptidase N-terminal domain and ring finger 3 | 711202 | ||||||
Mouse | MGI:1921615 | 74365 | ||||||
Rat | RGD:1565451 | 298322 | ||||||
Dog | LON peptidase N-terminal domain and ring finger 3 | VGNC:42736 | 100687354 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | LON peptidase N-terminal domain and ring finger 3 | |||||
Macaque | LON peptidase N-terminal domain and ring finger 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | LON peptidase N-terminal domain and ring finger 3 | |||||
Publication Statistics
PubMed Score 0.65
PubMed score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (1)
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