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Tdark
LNP1
Leukemia NUP98 fusion partner 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000383693
  • ENSP00000373191
  • ENSG00000206535

Symbol
  • NP3
  • NP3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.67
tissue sample
0.58
cellular component
0.48
tissue
0.46
transcription factor binding site profile
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 223.54   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 223.54   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
NUDT12
Tbio
Family:  Enzyme
Novelty:  0.18740719
p_int:  0.999955746
p_ni:  0.000044236
p_wrong:  1.8e-8
Data Source:  BioPlex
YWHAE
Tbio
Novelty:  0.00431876
p_int:  0.999846418
p_ni:  0.000153582
Data Source:  BioPlex
NDUFAF5
Tbio
Family:  Enzyme
Novelty:  0.13483499
p_int:  0.997554476
p_ni:  0.002445518
p_wrong:  7e-9
Data Source:  BioPlex
TRPC4AP
Tbio
Novelty:  0.02170224
p_int:  0.994678088
p_ni:  0.00454681
p_wrong:  0.000775102
Data Source:  BioPlex
YWHAG
Tchem
Novelty:  0.00845572
p_int:  0.992534034
p_ni:  0.007465966
Data Source:  BioPlex
YWHAH
Tchem
Novelty:  0.01000071
p_int:  0.981245747
p_ni:  0.018754253
Data Source:  BioPlex
YWHAZ
Tchem
Novelty:  0.00210582
p_int:  0.974379845
p_ni:  0.025620155
Data Source:  BioPlex
YWHAB
Tchem
Novelty:  0.00614093
p_int:  0.966455291
p_ni:  0.033544709
Data Source:  BioPlex
YWHAQ
Tchem
Novelty:  0.00234496
p_int:  0.918617143
p_ni:  0.081382857
Data Source:  BioPlex
PM20D2
Tdark
Family:  Enzyme
Novelty:  0.63491472
p_int:  0.909373844
p_ni:  0.090626156
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose measurement
1
1
1
48.5
refractive error measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose measurement
1
48.5
refractive error measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
leukemia NUP98 fusion partner 1
739703
Macaque
leukemia NUP98 fusion partner 1
700480
Rat
RGD:2323126
100359918
Dog
leukemia NUP98 fusion partner 1
478542
Horse
leukemia NUP98 fusion partner 1 [Source:HGNC Symbol;Acc:HGNC:28014]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
leukemia NUP98 fusion partner 1
Macaque
leukemia NUP98 fusion partner 1
Rat
Dog
leukemia NUP98 fusion partner 1
Horse
leukemia NUP98 fusion partner 1 [Source:HGNC Symbol;Acc:HGNC:28014]
Publication Statistics
PubMed Score 223.54
PubMed score by year
PubTator Score 38.01
PubTator score by year
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Related Publications
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PMID
Year
Title