LMLN
Leishmanolysin-like peptidase
Protein Summary
Metalloprotease. This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
- ENST00000330198
- ENSP00000328829
- ENSG00000185621
- ENST00000420910
- ENSP00000410926
- ENST00000482695
- ENSP00000418324
- INV
- MSP
- GP63
- IX14
- LMNL1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.72 | ||
transcription factor binding site profile | 0.69 | ||
transcription factor perturbation | 0.68 | ||
microRNA | 0.65 | ||
tissue sample | 0.65 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 400.19 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 25 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 400.19 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 25 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0