LIN7C
Protein lin-7 homolog C
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.98 | ||
transcription factor perturbation | 0.98 | ||
histone modification site profile | 0.91 | ||
kinase perturbation | 0.91 | ||
microRNA | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of NMDA receptors and postsynaptic events | ||||
Reactome | Assembly and cell surface presentation of NMDA receptors | ||||
Reactome | Dopamine Neurotransmitter Release Cycle | ||||
Reactome | Neurexins and neuroligins | ||||
Reactome | Neuronal System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of NMDA receptors and postsynaptic events | ||||
Assembly and cell surface presentation of NMDA receptors | ||||
Dopamine Neurotransmitter Release Cycle | ||||
Neurexins and neuroligins | ||||
Neuronal System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 1 | 3 | 3 | 87.7 | |||||
balding measurement | 1 | 2 | 2 | 82.4 | |||||
bone density | 3 | 2 | 7 | 72.7 | |||||
1 | 1 | 0 | 1.4 | 67.9 | |||||
hair color | 1 | 1 | 0 | 1.1 | 59 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 87.7 | |||||
balding measurement | 2 | 82.4 | |||||
bone density | 7 | 72.7 | |||||
0 | 1.4 | 67.9 | |||||
hair color | 0 | 1.1 | 59 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | lin-7 homolog C, crumbs cell polarity complex component | VGNC:7759 | 466475 | |||||
Macaque | lin-7 homolog C, crumbs cell polarity complex component | 698832 | ||||||
Mouse | MGI:1330839 | 22343 | ||||||
Rat | RGD:621164 | 60442 | ||||||
Horse | lin-7 homolog C, crumbs cell polarity complex component | VGNC:19680 | 100072314 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | lin-7 homolog C, crumbs cell polarity complex component | |||||
Macaque | lin-7 homolog C, crumbs cell polarity complex component | |||||
Mouse | ||||||
Rat | ||||||
Horse | lin-7 homolog C, crumbs cell polarity complex component | |||||
PMID | Year | Title |
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