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Tbio
LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Protein Summary
Description
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368839
  • ENSP00000357832
  • ENSG00000107902
  • ENST00000368842
  • ENSP00000357835

Symbol
  • HDHD2B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.83
histone modification site profile
0.76
molecular function
0.7
transcription factor binding site profile
0.67
phenotype
0.63


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.47   (req: < 5)
Gene RIFs: 27   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.47   (req: >= 5)
Gene RIFs: 27   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0