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Tbio
LGI2
Leucine-rich repeat LGI family member 2

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.8   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.8   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (47)
PARN
Tbio
Family:  Enzyme
Novelty:  0.00738516
p_int:  0.999997287
p_ni:  0.000002713
Data Source:  BioPlex
ADAM22
Tbio
Family:  Enzyme
Novelty:  0.01981755
Score:  0.973
Data Source:  Reactome,STRINGDB
ADAM23
Tbio
Family:  Enzyme
Novelty:  0.02974247
Score:  0.973
Data Source:  Reactome,STRINGDB
PM20D1
Tdark
Family:  Enzyme
Novelty:  0.07205788
Score:  0.714
Data Source:  STRINGDB
SLC17A3
Tbio
Family:  Transporter
Novelty:  0.04671795
Score:  0.696
Data Source:  STRINGDB
ADAM11
Tbio
Family:  Enzyme
Novelty:  0.122537
Score:  0.686
Data Source:  STRINGDB
CRHBP
Tbio
Novelty:  0.00726484
Score:  0.68
Data Source:  STRINGDB
FBXL17
Tbio
Novelty:  0.16122137
Score:  0.666
Data Source:  STRINGDB
SLC4A3
Tbio
Family:  Transporter
Novelty:  0.04796224
Score:  0.645
Data Source:  STRINGDB
FKBP5
Tchem
Family:  Enzyme
Novelty:  0.00214511
Score:  0.641
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
LGI-ADAM interactions
Name
Explore in Pharos
Explore in Source
Developmental Biology
LGI-ADAM interactions
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
1
1
22.8
neutrophil count
1
1
1
15.1
tonsillectomy risk measurement
1
1
0
1.1
10.2
gut microbiome measurement
1
1
1
3.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
22.8
neutrophil count
1
15.1
tonsillectomy risk measurement
0
1.1
10.2
gut microbiome measurement
1
3.2
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
leucine rich repeat LGI family member 2
693308
Mouse
MGI:2180196
246316
Rat
RGD:1310391
305417
Dog
leucine rich repeat LGI family member 2
VGNC:49726
488853
Horse
leucine rich repeat LGI family member 2
VGNC:19645
100067566
Species
Name
OMA
EggNOG
Inparanoid
Macaque
leucine rich repeat LGI family member 2
Mouse
Rat
Dog
leucine rich repeat LGI family member 2
Horse
leucine rich repeat LGI family member 2
Publication Statistics
PubMed Score 21.80
PubMed score by year
PubTator Score 7.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title