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Tdark
LENG1
Leukocyte receptor cluster member 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000222224
  • ENSP00000222224
  • ENSG00000105617
  • ENST00000610998
  • ENSP00000481386
  • ENSG00000276959
  • ENST00000613622
  • ENSP00000478485
  • ENSG00000278516
  • ENST00000616103
  • ENSP00000481252
  • ENSG00000277808
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.85
tissue sample
0.65
transcription factor
0.62
transcription factor binding site profile
0.58
cell type or tissue
0.52


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 171   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.71   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 171   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
YEATS4
Tbio
Novelty:  0.02632024
p_int:  0.994528959
p_ni:  0.005469028
p_wrong:  0.000002013
Score:  0.178
Data Source:  BioPlex,STRINGDB
ESS2
Tbio
Novelty:  0.00163665
p_int:  0.988441579
p_ni:  0.01142386
p_wrong:  0.00013456
Score:  0.596
Data Source:  BioPlex,STRINGDB
TRIM68
Tbio
Family:  Enzyme
Novelty:  0.11729189
p_int:  0.98797066
p_ni:  0.012029336
p_wrong:  5e-9
Score:  0.193
Data Source:  BioPlex,STRINGDB
LRRC3B
Tbio
Novelty:  0.05929142
p_int:  0.972068054
p_ni:  0.021227923
p_wrong:  0.006704023
Data Source:  BioPlex
CCR1
Tchem
Family:  GPCR
Novelty:  0.00218065
p_int:  0.914374059
p_ni:  0.001874277
p_wrong:  0.083751665
Score:  0.232
Data Source:  BioPlex,STRINGDB
FRA10AC1
Tdark
Novelty:  0.25570773
p_int:  0.858797911
p_ni:  0.14112967
p_wrong:  0.000072419
Score:  0.826
Data Source:  BioPlex,STRINGDB
MBOAT7
Tbio
Family:  Enzyme
Novelty:  0.01861411
Score:  0.823
Data Source:  STRINGDB
PPIL1
Tbio
Family:  Enzyme
Novelty:  0.08004386
Score:  0.732
Data Source:  STRINGDB
TSEN34
Tdark
Family:  Enzyme
Novelty:  0.06726323
Score:  0.724
Data Source:  STRINGDB
SNRPF
Tdark
Novelty:  0.17624854
Score:  0.717
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (304)
Items per page:
1 – 5 of 304
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
3
3
18.1
97.7
alkaline phosphatase measurement
2
3
3
18.1
97.7
alkaline phosphatase measurement
2
3
3
18.1
97.7
alkaline phosphatase measurement
2
3
3
18.1
97.7
creatine kinase measurement
5
4
8
96.6
Items per page:
1 – 5 of 304
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
3
18.1
97.7
alkaline phosphatase measurement
3
18.1
97.7
alkaline phosphatase measurement
3
18.1
97.7
alkaline phosphatase measurement
3
18.1
97.7
creatine kinase measurement
8
96.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
leukocyte receptor cluster member 1
693417
Mouse
MGI:1917007
69757
Rat
RGD:1307933
292535
Dog
leukocyte receptor cluster member 1
VGNC:42635
476388
Horse
leukocyte receptor cluster member 1
VGNC:19629
100052583
Species
Name
OMA
EggNOG
Inparanoid
Macaque
leukocyte receptor cluster member 1
Mouse
Rat
Dog
leukocyte receptor cluster member 1
Horse
leukocyte receptor cluster member 1
Publication Statistics
PubMed Score 0.71
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title