LEMD3
Inner nuclear membrane protein Man1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.76 | ||
interacting protein | 0.75 | ||
microRNA | 0.75 | ||
cellular component | 0.7 | ||
kinase perturbation | 0.6 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | Depolymerisation of the Nuclear Lamina | ||||
Reactome | Initiation of Nuclear Envelope Reformation | ||||
Reactome | M Phase | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
Depolymerisation of the Nuclear Lamina | ||||
Initiation of Nuclear Envelope Reformation | ||||
M Phase | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hippocampal CA1 volume | 2 | 1 | 0 | 14 | 78.5 | ||||
granule cell layer dentate gyrus volume | 1 | 1 | 0 | 8.8 | 73.5 | ||||
hippocampal CA4 volume | 1 | 1 | 0 | 7.3 | 71.5 | ||||
hippocampal CA3 volume | 1 | 1 | 0 | 7.8 | 70.8 | ||||
presubiculum volume | 1 | 1 | 0 | 5.6 | 64.4 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hippocampal CA1 volume | 0 | 14 | 78.5 | ||||
granule cell layer dentate gyrus volume | 0 | 8.8 | 73.5 | ||||
hippocampal CA4 volume | 0 | 7.3 | 71.5 | ||||
hippocampal CA3 volume | 0 | 7.8 | 70.8 | ||||
presubiculum volume | 0 | 5.6 | 64.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | LEM domain containing 3 | VGNC:5450 | 452050 | |||||
Macaque | LEM domain containing 3 | 717597 | ||||||
Mouse | MGI:3580376 | 380664 | ||||||
Rat | RGD:1596822 | 680066 | ||||||
Dog | LEM domain containing 3 | VGNC:42633 | 608380 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | LEM domain containing 3 | |||||
Macaque | LEM domain containing 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | LEM domain containing 3 | |||||
PMID | Year | Title |
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