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Tbio
LEMD1
LEM domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367149
  • ENSP00000356117
  • ENSG00000186007
  • ENST00000367151
  • ENSP00000356119
  • ENST00000367152
  • ENSP00000356120
  • ENST00000367153
  • ENSP00000356121
  • ENST00000367154
  • ENSP00000356122
  • ENST00000391936
  • ENSP00000375801
  • ENST00000495594
  • ENSP00000479306

Symbol
  • CT50
  • LEMP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.68
PubMedID
0.64
transcription factor
0.59
trait
0.46
gene perturbation
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 73.59   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 73.59   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
LEXM
Tbio
Novelty:  0.06476414
Score:  0.9
Data Source:  STRINGDB
BANF1
Tbio
Novelty:  0.00092814
Score:  0.705
Data Source:  STRINGDB
LEMD3
Tbio
Novelty:  0.00579701
Score:  0.655
Data Source:  STRINGDB
PMM2
Tchem
Family:  Enzyme
Novelty:  0.01177513
Score:  0.644
Data Source:  STRINGDB
TRIP12
Tbio
Family:  Enzyme
Novelty:  0.03433452
Score:  0.626
Data Source:  STRINGDB
FBXO39
Tbio
Novelty:  0.05342001
Score:  0.612
Data Source:  STRINGDB
SENP8
Tchem
Family:  Enzyme
Novelty:  0.00774396
Score:  0.584
Data Source:  STRINGDB
CCDC110
Tbio
Novelty:  0.11479518
Score:  0.547
Data Source:  STRINGDB
LEMD2
Tbio
Novelty:  0.12460123
Score:  0.487
Data Source:  STRINGDB
CCDC33
Tdark
Novelty:  0.17166818
Score:  0.485
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
2
2
72.7
bowel opening frequency
1
1
1
41.8
blood urea nitrogen measurement
1
1
1
32.2
sleep measurement
1
1
1
11.4
serum gamma-glutamyl transferase measurement
2
1
2
10.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
2
72.7
bowel opening frequency
1
41.8
blood urea nitrogen measurement
1
32.2
sleep measurement
1
11.4
serum gamma-glutamyl transferase measurement
2
10.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
LEM domain containing 1
VGNC:6906
743044
Mouse
MGI:1922403
213409
Dog
LEM domain containing 1
VGNC:42631
100685521
Horse
LEM domain containing 1
VGNC:19628
100629583
Cow
LEM domain containing 1
VGNC:30835
767969
Species
Name
OMA
EggNOG
Inparanoid
Chimp
LEM domain containing 1
Mouse
Dog
LEM domain containing 1
Horse
LEM domain containing 1
Cow
LEM domain containing 1
Publication Statistics
PubMed Score 73.59
PubMed score by year
PubTator Score 17.88
PubTator score by year
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Related Publications
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PMID
Year
Title