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Tbio
LCN6
Epididymal-specific lipocalin-6

Protein Summary
Description
May play a role in male fertility.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341206
  • ENSP00000339621
  • ENSG00000267206

Symbol
  • LCN5
  • LCN5
  • hLcn5
  • UNQ643
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
protein domain
0.58
cell line
0.43
tissue sample
0.34
biological term
0.33


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.65   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.65   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (72)
CTSF
Tchem
Family:  Enzyme
Novelty:  0.01359417
p_int:  0.999899595
p_ni:  0.000100405
Data Source:  BioPlex
LMLN
Tdark
Family:  Enzyme
Novelty:  0.00289803
p_int:  0.999716651
p_ni:  0.000218061
p_wrong:  0.000065288
Data Source:  BioPlex
RTN4RL2
Tbio
Novelty:  0.05919593
p_int:  0.999687921
p_ni:  0.000203472
p_wrong:  0.000108608
Data Source:  BioPlex
SEMA4D
Tbio
Novelty:  0.0043592
p_int:  0.999506993
p_ni:  0.00036848
p_wrong:  0.000124527
Data Source:  BioPlex
CEMIP2
Tbio
Novelty:  0.04698236
p_int:  0.999424181
p_ni:  0.000575817
p_wrong:  2e-9
Data Source:  BioPlex
GLB1L
Tdark
Family:  Enzyme
Novelty:  0.43027328
p_int:  0.998079176
p_ni:  0.001693583
p_wrong:  0.000227241
Data Source:  BioPlex
SERPINE2
Tbio
Novelty:  0.00246375
p_int:  0.99782487
p_ni:  0.00217513
Data Source:  BioPlex
NDST1
Tbio
Family:  Enzyme
Novelty:  0.00955868
p_int:  0.997584954
p_ni:  0.002414851
p_wrong:  1.95e-7
Data Source:  BioPlex
C15orf39
Tdark
Novelty:  1.68615093
p_int:  0.995556153
p_ni:  0.004443808
p_wrong:  3.9e-8
Data Source:  BioPlex
CHSY3
Tdark
Family:  Enzyme
Novelty:  0.17103933
p_int:  0.994897916
p_ni:  0.005100764
p_wrong:  0.00000132
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
1
1
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
38.8
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 8.65
PubMed score by year
PubTator Score 5.57
PubTator score by year
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Related Publications
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PMID
Year
Title