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Tdark
LCHN
Protein LCHN

Protein Summary
Description
May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000536163
  • ENSP00000445768
  • ENSG00000257093
  • ENST00000575464
  • ENSP00000459381
  • ENSG00000262599

Symbol
  • KIAA1147
  • LCHN
  • PRO2561
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.84
cell type or tissue
0.81
microRNA
0.68
virus perturbation
0.68
histone modification site profile
0.66


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.58   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.58   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
DKKL1
Tbio
Novelty:  0.00544618
p_int:  0.998181986
p_ni:  0.001818014
Data Source:  BioPlex
EFNB3
Tbio
Novelty:  0.0120367
p_int:  0.982232335
p_ni:  0.017767665
Score:  0.165
Data Source:  BioPlex,STRINGDB
KLK11
Tbio
Family:  Enzyme
Novelty:  0.00267977
p_int:  0.981516893
p_ni:  0.018483107
Score:  0.188
Data Source:  BioPlex,STRINGDB
KLK5
Tchem
Family:  Enzyme
Novelty:  0.00835407
p_int:  0.976957538
p_ni:  0.023042462
Score:  0.175
Data Source:  BioPlex,STRINGDB
CSTL1
Tbio
Novelty:  0.13370814
p_int:  0.974938587
p_ni:  0.025061413
Data Source:  BioPlex
KLK15
Tbio
Family:  Enzyme
Novelty:  0.00083978
p_int:  0.932656953
p_ni:  0.067343047
Data Source:  BioPlex
TGOLN2
Tbio
Novelty:  0.005107
p_int:  0.755853816
p_ni:  0.244146184
Score:  0.179
Data Source:  BioPlex,STRINGDB
AVL9
Tbio
Novelty:  0.14044287
Score:  0.925
Data Source:  STRINGDB
DENND6A
Tbio
Novelty:  4.5572617
Score:  0.907
Data Source:  STRINGDB
FAM45A
Tdark
Novelty:  0.94034891
Score:  0.907
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
64.4
1
1
1
64.4
Items per page:
1 – 2 of 2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
64.4
1
64.4
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 13.58
PubMed score by year
PubTator Score 2.11
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title