Tbio LCE1B Late cornified envelope protein 1B

Protein Summary

Description

Precursors of the cornified envelope of the stratum corneum.

Uniprot Accession IDs

• Q5T7P3
• A4IF40

Gene Name

• LCE1B

Ensembl ID

• ENST00000360090
• ENSP00000353203
• ENSG00000196734

Symbol

• LEP2
• SPRL2A
• LEP2
• SPRL2A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue	0.68
cell line	0.45
biological term	0.33
tissue sample	0.32
protein domain	0.26

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.75   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 52   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.75   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0